Deal With Cancer - dealwithcancer.com

[...] post Myostatin gene inactivation prevents skeletal muscle wasting cancer appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] responses and the activation of T cells in the tumor microenvironment appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] in the 3’UTR of CXCR2 that is associated with reduced risk of lung cancer appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] of the Philadelphia suburbs, and raised nearly $2 million for cancer research at the Abramson Cancer Center. In this post, Abramson Cancer Center Director Chi Van Dang, MD, PhD, shares his [...]

[...] JFM Memorial Gala to honor his father’s life, share the treatment he received at Abramson Cancer Center of the University of Pennsylvania by Charles B. Simone II, MD and to inspire hope. The [...]

[...] In 2011, Kimberly Fink was treated at the Abramson Cancer Center for uterine cancer. Once her treatment ended, Kimberly came up with the idea for [...]

[...] The Abramson Cancer Center is proud to recognize November as Lung Cancer Awareness Month. As smoking is one of the [...]

[...] ... continue reading The post VEGF targeted therapy stably modulates the glycolytic phenotype of tumor cells appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] A inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] Clinical cancer dormancy is evident from the detection of circulating tumor cells in the blood and tissue-residing disseminated tumor cells in the bone marrow of cancer [...]

[...] An important aspect of malignant progression is the acquired ability of tumor cells to avoid recognition and destruction by the immune system (immune escape). Clinical cancer [...]

[...] NF-{kappa}B is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] (TUBB3) expression is associated with therapeutic resistance and aggressive disease in non-small cell lung cancer (NSCLC), but the basis for its pathogenic influence is not understood. Functional and [...]

[...] mutation of p53 and suppression of the miR-17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D signaling appeared first on Deal With Cancer - [...]

[...] even more personal. His father, Joseph F. McNichol, was diagnosed with Stage IV, non-small cell lung cancer— sadly losing his battle only a year later, in July 2012. “Lung cancer is [...]

[...] reading The post Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] post RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid tumors. Likewise, the tumor microenvironment contributes critical support in t... continue reading The post ISG15 is a critical [...]

[...] post PD-1/SHP-2 inhibit Tc1/Th1 phenotypic responses and the activation of T cells in the tumor microenvironment appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] The post In vivo radioimaging of bradykinin receptor B1, a widely overexpressed molecule in human cancer appeared first on Deal With Cancer - dealwithcancer.com. [...]

[...] MicroRNA (miRNA) dysregulation contributes widely to human cancer but has not been fully assessed in oral cancers. In this study, we conducted a global [...]

[...] cell growth by inhibiting cyclin-dependent kinases. Cables1 expression is lost frequently in human cancer but little is known about its regulation. Here we report that Cables1 levels are... continue [...]

[...] -30% of all non-small cell lung cancers (NSCLC) are associated with chemoresistance and poor prognosis. Here we demonstrate that activation of the cell protective stress response gene NRF2 [...]

[...] common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically [...]

[...] The prototypic chitinase-like protein Chi3l1 is induced in cancers and portends a poor prognosis, but whether it contributes to cancer progression is unknown. To address this gap in [...]